TikTok Series: Breast Development

Boobs! Breast development is a hot topic in gender affirming care, and there are a lot of unknowns about optimizing breast development.

We believe that there is no one way to be trans, and that includes each person’s body goals. For people who want breast development, we believe that adding progesterone to the medication regiment supports fuller breast development. Here’s Dr. Beal talking about it in a QueerCME tiktok – please remember that Queer CME is directed at clinicians and prescribers, and not patients, so the language is often a little different than how we would discuss breast development in an appointment with a patient.

Other QueerDoc Info On Progesterone and Breast Development:

QueerCME tiktok on Breast Development:

originally posted 12/3/2023

Video Transcript

let’s talk about uh

the timeline for breast development

I’ll talk more about progesterone this upcoming week um

but someone asked uh

timeline questions

and I wanna take some time to go over this

cause I think clinicians

setting realistic expectations for patients seeking gender affirming care

is one of the most important jobs or roles we have um remember

gender affirming care is a little different than a lot of the rest of healthcare

um because gender diversity is not a disease or pathology um right

it’s an identity

and we’re supporting people being who they are and so uh

this is less about being the paternalistic expert and more about supporting um

people having the information to make the right choices for themselves

and so I think expectation setting is a very important part of that and so

timeline for breast development and expectations around breast development

your patient should start to experience breast budding

typically within three to six months of gender affirming hormone therapy

starting with estrogen um

and we expect to see the bulk of breast development completed within two years

um a lot of times you’ll see you know

the vast majority of it in the first 18 months

and the changes after that

are more subtle

and after two years

you can continue to see subtle changes

particularly if your body changes size right

weight gain definitely affects breast size

but it’s gonna be much more subtle than what you saw in the first 18

months to two years in that patient

there is a lot that is unknown about breast development

and trans and gender diverse patients um

and there tends to be a

a fair amount of dissatisfaction

when we look at the literature with breast development

which is interesting because breast size is actually fairly similar um

to average breast size in ciswomen

um I think part of the issue is um

the same size breasts are sitting on a larger chest

right so chest width, rib cage size are larger in patients who are

in people who have had a testosterone based puberty first

and so um even though the amount of breast tissue present

is similar to what we see in ciswomen

um it looks proportionally smaller because of the size chest it’s on

um also because of that chest width

it tends to set a little further apart um

and so you don’t get the same kind of cleavage response um

that two years is actually kind of important

if patients are interested in breast augmentation

if patients are interested in breast augmentation

and are considering estrogen therapy or gonna do estrogen therapy

the general recommendation is to wait for two years of estrogen therapy

um so that the implants can be placed appropriately

according to how the breast develop

um right if we put them in sooner than that

the surgeon can’t account for that uh

upcoming breast tissue development

and so the aesthetics might long term might not be quite as ideal um

as far as like

the one best approach in gender affirming care for breast development

as far as we know

that doesn’t exist

we don’t have any peer reviewed literatures or studies saying that um

estrogen done this way or estrogen with this anti androgen is better

um there is some literature that suggests patients who take spironolactone

are more likely to seek breast augmentation later

um so that might be associated with like um

potentially earlier breastbud fusion

there’s also um

evidence that suggests uh

too high of an estrogen dose too fast can lead to um

earlier breastfed fusion as well

and thus stunted or a decrease development or growth um

this kind of circles to around some of Powers like approaches

cause he kind of has this idea

this recipe maybe that is like there’s one best approach for everyone

I don’t think that’s true

I think the best approach for gender affirming care is individualized

off of many many issues

but primarily pre existing health conditions

um goals for care um

values and access um

that being said

my clinicians at my clinic sometimes joke

about something they called the Beal method and

I’m not the only clinician who thought of this right

but testosterone has a stunting effect on breast development as well and

and we know that a too high dose of estrogen too fast

stunts breast development in

so theoretically

if we could really successfully block testosterone

and do a much more gradual approach with estrogen dosing

much more similar to what we see in a cis-based ovarian puberty um

there’s some thoughts that we might have

like matter better or more predominant breast development

and so that you know

really looks like trying to access a GnRH agonist um

or orchiectomy um

which isn’t necessarily accessible for most people

a lot of patients aren’t necessarily at a point

and their experience with their want to access orchectomy

like before they start estrogen um

and GnRH agonists

a lot of times are cost inaccessible for patients um

a lot of times you have to fail uh

you know oral anti antigens before an insurance will prior auth GnRH agonists

um and for patients without insurance

they’re you know

not accessible at all except from international pharmacies

typically because they’re thousands of dollars um

I have heard FQHC

so nonprofit pharmacies have them for a cheaper

and so that’s like 100 bucks a month instead of thousands of bucks a month

so that’s something to consider

um yeah to be clear

all of this is theory

none of this is proven

um and frankly

the way we would try to prove things like this would potentially be twin studies

um which obviously have a lot of barriers

issues and ethics around them um

but based off of what we currently know

that is like how I would think about

theoretically trying to optimize breast development

I would also incorporate progesterone um

I think it’s absolutely essential for the development of a mature breast

and what we do see in the literature about um

breasts on trans people taking estrogen is that they rarely reach Tanner stage 5

and I think that’s because progesterone

has been left out of gender affirming care

um so much and

and so I do think it’s an essential component

um the other thing you know

we see in the literature is that breast development varies widely

um in a few studies have actually said it’s independent of the estrogen dose

um which again

harkens back to this idea that like

if there is one best way

to approach gender affirming care with estrogen for breast development

we certainly don’t know what it is yet um

yeah so to answer that question

um breast budding starts within the first three to six months

of taking estrogen um

and like you know

kind of the maturation or completion of breast development on estrogen

is mostly gonna happen within the first two years

you’ll see more subtle changes after that um

and I think for optimizing breast development

progesterone is really important

um most of my patients are not on spironolactone

I have had more lately on spironolactone

cause I’m getting a lot of transfers of care um

because everything is happening in Florida um um

I clinicians am not a big fan of spironolactone um

not necessarily because of that literature about breast development

although if a patient has um

breast development and physical expression as some of their big goals

I’m always gonna be talking about that with them

um I’m less a fan of it because it’s a diuretic and um

being a trans person

trying to use public restrooms um

even in like

really urban areas that are like

generally more affirming

even there it’s hard

um and so anywhere outside of that fucking sucks

and I just don’t wanna give um

patient something

that’s gonna have to make them access public restrooms more often

if I can avoid it um yeah

thoughts about breast development

and hopefully that answered your question


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